Hurricane Isaias makes landfall near Destin, Florida, as a Category 2 storm with winds of 105 mph; destructive 7.7 magnitude quake topples buildings in Panama; NFL legend Mike Ditka dies at 86.  

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Communities on the Gulf Coast are preparing for Hurricane Isaias, now a Category 3 storm, to make landfall. ABC News’ Leslie Lopez has the latest from Mobile Bay, Alabama.
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Maha Elbanna talks about her journey to Egypt.

Israel-Hamas conflict live updates: https://tinyurl.com/2382ufmf

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Paul Bettany talks ‘VisionQuest’; Hurricane Isaias closes in on Gulf Coast; Emotional reunions as USS Abraham Lincoln returns home

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Russian authorities have quarantined a hospital and are monitoring contacts of an employee at a plague research institute in Siberia who contracted pneumonia of an “unknown” cause.

ABC News’ Elizabeth Schulze and Dr. Darien Sutton report.

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