The US launched a new wave of strikes against Iran on Tuesday evening, according to a US Central Command social media post. The strikes began at 5 p.m. EDT, according to the post, and are “in response to yesterday’s downing of a US Army Apache helicopter” off the coast of Oman. The command characterized the attacks as “self-defense strikes.”

Iran has launched missiles and drones toward US targets in the region, the Islamic Revolutionary Guard Corps (IRGC) said in a Telegram post early Wednesday local time.

0:00 US attacks Iran for downed Apache; Iran retaliates
1:56 Senior WH Correspondent on future strikes, peace deal
3:00 Retired Adm. McRaven on how to open the Strait of Hormuz
5:39 Adm. McRaven reacts to Trump, Hegseth’s war rhetoric

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ABC News’ Diane Macedo is joined by Adam Keehn, director of complex emergencies for Americares, to discuss how his organization is aiding Ukrainian refugees with medical and relief supplies.

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Former Republican presidential candidate Chris Christie weighs in on Ohio Republican gubernatorial candidate Vivek Ramaswamy and the state’s governor’s race.

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Texas Rep. Michael McCaul doesn’t want a U.S.-imposed no-fly zone over Ukraine but says the U.S. needs to be ready to respond appropriately if Russia uses chemical weapons.

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BREAKING: President Trump announced in a social media post that chief of staff Susie Wiles is out at the White House and his top aide Stephen Miller will replace her in the job. https://abcnews.com/Politics/trump-chief-staff-susie-wiles-miller-replace/story?id=137921244

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